IGF-1 LR3
IGF-1 LR3
IGF-1 LR3
IGF-1 LR3
Prodigy Peptides

IGF-1 LR3

$49.99
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IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3)

Advanced Anabolic & Regenerative Research Compound

Product Overview

IGF-1 LR3 is a synthetic, 83-amino acid analogue of human insulin-like growth factor-1 (IGF-1). It is modified with an arginine substitution at position 3 and a 13-amino-acid N-terminal extension, which prevents it from binding to IGF-binding proteins (IGFBPs). This results in a significantly extended half-life of 20–30 hours and increased biological potency compared to native IGF-1. Researchers utilize IGF-1 LR3 to investigate muscle hypertrophy, cellular proliferation, and metabolic energy dynamics.

Key Research Applications

  • Muscle Hypertrophy & Repair: Widely studied for its ability to stimulate satellite cell activation and enhance protein synthesis in skeletal muscle models.

  • Regenerative Science: Evaluated in research regarding the repair of tendons, ligaments, and connective tissues.

  • Metabolic Regulation: Investigated for its influence on glucose uptake and amino acid transport within various cellular models.

  • Cellular Proliferation: Serves as a primary tool for exploring signaling cascades like the PI3K-AKT and MAPK pathways associated with cell growth and survival.

  • Neurotrophic Studies: Evaluated for its potential to support neuronal survival and synaptic plasticity through its interaction with the IGF-1 receptor.

Why Researchers Choose IGF-1 LR3

  • Superior Potency: Approximately three times more potent than native IGF-1 due to reduced binding with inhibitory proteins.

  • Extended Half-Life: Features a prolonged elimination half-life of 20–30 hours, allowing for sustained biological activity in experimental settings.

  • High Analytical Purity: Verified to be ≥95% pure (typically via SDS-PAGE and HPLC) to ensure consistent and reproducible research data.

  • Experimental Versatility: Suitable for a broad range of applications, from stem cell culture maintenance to musculoskeletal and neural studies.

Technical Specifications

Research Notice: IGF-1 LR3 is strictly for laboratory and scientific research use only. Not for human or animal consumption, medical treatment, or therapeutic use.

Validated Synthesis & Expedited Fulfillment

Clinical-Grade Synthesis & Purity


Our RUO peptides are engineered via precision synthesis, utilizing meticulously validated protocols to ensure uncompromising accuracy and batch-to-batch consistency. To maintain verified purity, every production lot undergoes independent third-party analysis—including HPLC and mass spectrometry—to confirm molecular identity and a purity of >98%. For expedited research timelines, we provide same-day fulfillment from our U.S. facility, ensuring rapid and reliable delivery of all orders.

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